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This article reviews the best dosages for CoQ10 depending on your needs. What Is CoQ10? Share on Pinterest. Dosage Recommendations by Health Condition. Side Effects. The Bottom Line. Read this next. The Surprising Truth. Magnesium for Migraines When taken in safe doses, magnesium can effectively prevent migraines for many people.
Join now at www. I recently bought a CoQ10 supplement on Amazon. The manufacture date was hidden under a sticker, but was 13 months ago. No "Best By" date is listed. Is this product still good to use?
Can I take CoQ10 at the same time as my statin, or should I take them separately? Is it safe to take CoQ10 while taking blood thinners like warfarin or Plavix clopidogrel? I take ubiquinol to replenish CoQ10 depleted by my statin. I also take curcumin from turmeric. Since they both manage free radicals, do I need to take the curcumin?
Is MitoQ a better form of CoQ10? MitoQ information, including how it is absorbed in the body and how it compares to CoQ Could my CoQ10 supplement be making me nauseous?
Could my CoQ10 supplement be causing my insomnia? Does taking natural versus synthetic CoQ10 make a difference? How do you know which product is natural or synthetic?
Natural CoQ10 compared to synthetic CoQ10 supplements. Learn the differences. Do I need to divide my daily mg dose of CoQ10 into smaller doses, or can I take it all at once? How do I choose the best CoQ10 supplement? What is the difference between CoQ10 and ubiquinol?
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Continue to Join. Join the conversation. Submit comment Saving…. Niela January 15, L April 4, Helen January 15, Alexandra April 4, CoQ10 plays a vital role in energy production and DNA replication and repair. It also acts as an antioxidant , neutralizing harmful free radicals. For the body to use CoQ10, it must convert it from its inactive form, ubiquinone, into it its active form, ubiquinol.
This process is known as ATP synthesis. Under normal conditions, free radicals regulate communication between cells and defend the body against infectious microbes. However, excess free radicals cause DNA damage, which can lead to the following:. CoQ10 acts as an antioxidant by neutralizing free radicals. Standard daily doses of CoQ10 range from 60 milligrams mg to mg. The highest recommended dose is 1, mg.
However, clinical trials have used dosages as high as 3, mg per day. Different types of CoQ10 supplements may also require different dosages. Most supplements contain the inactive form of CoQ10, ubiquinone, which is harder to absorb than ubiquinol. A randomized trial compared the effects of mg daily doses of ubiquinone and ubiquinol supplements on CoQ10 levels in older men.
Ubiquinol supplementation led to a 1. Supplements containing ubiquinone did not have a significant effect on CoQ10 levels. CoQ10 protects cells against oxidative damage.
CoQ10 could, therefore, provide a range of health benefits. Some examples include:. The heart contains some of the highest concentrations of CoQ10 in the body. The vast majority of people with heart disease also have low CoQ10 levels. Researchers now consider low CoQ10 levels to be an indicator of the severity and long term outcome of various heart diseases.
In one pilot study , ten children with cardiac muscle dysfunction received — mg of liquid ubiquinol per day. At weeks 12 and 24 of treatment, the children had significantly higher CoQ10 plasma levels and improved heart function.
Cardiovascular disease CVD is an umbrella term for conditions that affect the heart or blood vessels. Doctors often prescribe statins to treat CVD. These drugs work by reducing the cholesterol production that can contribute to the disease. With CoQ10 supplements there is reasonable correlation between increase in plasma CoQ10 and ingested dose up to a certain point. Animal data show that CoQ10 in large doses is taken up by all tissues including heart and brain mitochondria.
This has implications for therapeutic applications in human diseases, and there is evidence for its beneficial effect in cardiovascular and neurodegenerative diseases.
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